Friday, February 14, 2020

Criticlly assess the basis of obedience by states in international Assignment

Criticlly assess the basis of obedience by states in international law. What factors do states take into account in compliance with international law rules - Assignment Example nal protocol faces the most potent challenge of embracing of the formulated laws and sustenance of the appropriate adherence across the member states (Alter, 19). While the membership of the international community has evolved in the recent past to be synonymous with the most acceptable yardstick for development, there are several considerations that make the expected transition the challenge it is today. The platform on which the international law is founded outlines the integrity of the leadership and governance of the international community and is built on commitment to comply with the binding regulations. Due to the unavailability of a political structure at such a level, only goodwill can be applied in the delivery of the commitment expected for compliance and adherence. In such an arrangement, it is evident that there are loopholes which expose the sovereignties of individual member states to the mercy of external forces. External interference is a contradiction to the existence of the member states as sovereign states, which is the predominant building block of the international community. In the protection of the integrity of the individual state and the international community, there is undoubted favor for the integrity of the member state sovereignty which is the basic unit of the international community. In light of conflicting interests and objectives as expected in such an arrangement, there are important considerations to be made by the leadership of the individual member states regarding becoming signatories of the effective protocols as well as the details of compliance. State behavior in embracing international law and handling international relations is important in determining the considerations that are likely to be highlighted by various leaderships before making commitment to such undertakings (Raustiala and Slaughter, 544). While politics therefore becomes central to the nature of state behavior detailing embracing international laws,

Saturday, February 1, 2020

Wegener's Granulomatosis Research Paper Example | Topics and Well Written Essays - 2250 words

Wegener's Granulomatosis - Research Paper Example Wegener’s granulomatis has no known cause and although it affects people at any age, it usually affects the young or adults at their middle age. Fatigue, loss of weight, fever, shortness of breath, bloody sputum, joint pain, and inflammation in the sinuses are the common symptoms of Wegener’s granulomatosis. Several literatures are reviewed in this paper. Among patients with Wegener granulomatosis, narrowing of the lumen with some evidence of vasculitis resulted from thickened or fibrotic laryngeal wall. In some cases, granulation tissue replaces the mucosal lining of the larynx. Hence, laryngoscopy must be carefully performed to avoid bleeding from granulomas and dislodgement of ulcerations tissue among patients whom suspected diagnosis of Wegener granulomatosis is noted. Wegener’s granulomatosis is a fatal disease when it is not diagnosed and treated properly since it presents in various forms and deceives as manifestations of other diseases. Annotated Bibliogr aphy 1. Tanna, et al., (2011) Otolaryngologic Manifestations of Wegener Granulomatosis (WG) This article discusses that it is common to have otolaryngologic manifestation among patients with Wegener granulomatosis, and usually presents as nasal, sinus, ear, or tracheal manifestations in about 70 percent. The symptoms of otolaryngologic manifestations are oftentimes misdiagnosed as infectious or allergic in etiology and generally precede the pulmonary or renal involvement. On the other hand, up to 80 percent of nose and paranasal sinuses are involved in WG and in its early stage, are often misdiagnosed as chronic rhinitis or sinusitis. Mucosal edema with obstruction, rhinorrhea, ulceration, crusting, and epistaxis are common nasal signs and symptoms observed in WG. It is mentioned in this article that necrotizing granulomatous inflammation of upper and lower airways, small arteries and veins systemic vasculitis, and focal granulomatous are known as the classical triad of full  œ blown granulomatosis. However, it is noted that it does necessarily involve all three areas and organ systems. Hence, both could be limited and systemic variations may include in the head and neck alone; head and neck and pulmonary; and head, neck, pulmonary and renal, which can be indolent or rapid in its clinical course. Its constitutional signs and symptoms, which are common but dominate rarely the clinical picture, include fever, loss of weight, and fatigue. 2. Goritsas, C., Paissios, N., Trigidou, R., and Delladetsima, J. (2010). Hepatic Involvement in Wegener’s Granulomatosis: A Case Report. This paper talks about the hepatic involvement in a patient diagnosed to have Wegener’s Granulomatosis. This is a case report of a 58 year old man, Caucasian Greek presenting with dry cough, fever, bilateral alveolar infiltrates, and acute hepatitis. The patient was diagnosed with Wegener’s granulomatosis after a lung biopsy, and its diagnosis was supported by anti-p roteinase-3 anti-neutrophil cytoplasmic antibodies present. Liver biopsy indicated a â€Å"presence of mild non-specific lobular hepatitis and periodic acid-Schiff positive Lafora-like inclusions in a large number of his liver cells.† Patient had remissions of chest x-ray findings and liver function test after being treated with prednisone and cyclophosphamide. The authors of this paper concluded that there is an etiological link between hepatitis and